Roma have been the stronger side in Serie A this season, with a seven-point advantage over Napoli after seven rounds. Gasperini's team remain unbeaten and have conceded just three goals, while Napoli have already suffered three league defeats.
The hosts showed improvement against Bodø/Glimt, but conceding three goals at home remains a concern. Their finishing has also been inconsistent, despite creating plenty of opportunities in recent matches.
Roma's injury problems cannot be ignored, particularly in midfield, but the return of Malen and the possible availability of Cristante should provide Gasperini with more options.
Napoli's strong home record against Roma makes an outright away victory a difficult call. Nevertheless, the visitors have been considerably more reliable in the league and have yet to concede an away goal this season.
We are backing Roma to win with a handicap of "0" at odds of 1.80. This selection offers protection if the match ends in a draw, while Roma's stronger recent results support the visitors' chances of taking all three points.
Napoli - Roma: key statistics and trends
Napoli have won only two of their last six Serie A matches
Both teams have scored in 43% of Napoli's matches, with an average total of 2.43 goals per game
Roma have failed to win only twice in this league campaign
Both teams have scored in 29% of Roma's matches, with an average total of 2.71 goals per game
Napoli - Roma: possible starting lineups
Napoli (4-3-3): Meret – Di Lorenzo, Rafa Marín, Badiashile, Olivera – De Bruyne, Lobotka, McTominay – Politano, Højlund, Lang.
Roma (3-4-1-2): Gollini – Mancini, Ndicka, Hermoso – Lulli, De Roon, Pisilli, Wesley – Cristante – Soulé, Malen.